Welcome to the MetGENE Tool

Given one or more genes, the MetGENE tool identifies associations between the gene(s) and the metabolites that are biosynthesized, metabolized, or transported by proteins coded by the genes. The gene(s) link to metabolites, the chemical transformations involving the metabolites through gene-specified proteins/enzymes, the functional association of these gene-associated metabolites and the pathways involving these metabolites.

The user can specify the gene using a multiplicity of IDs and gene ID conversion tool translates these into harmonized IDs that are basis at the computational end for metabolite associations. Further, all studies involving the metabolites associated with the gene-coded proteins, as present in the Metabolomics Workbench (MW), the portal for the NIH Common Fund National Metabolomics Data Repository (NMDR), will be accessible to the user through the portal interface. The user can begin her/his journey from the NIH Common Fund Data Ecosystem (CFDE) portal. A tutorial for MetGENE is available here.

Use separator "," for multiple gene symbols or IDs".

Gene_ID:

Gene-ID Type: SYMBOL SYMBOL_OR_ALIAS ENTREZID ENSEMBL REFSEQ UNIPROT

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Human Mouse Rat	Select anatomy/Sample source 293T HEK cell line A549 cells Acorns Adherent cell lines Adherent cultured mammalian cells Adipocyte media Adipocytes Adipose tissue Adipose Tissue, Liver Adrenal gland Algae Algae oil AML cells Amniotic fluid Aortic valve tissue Apoplastic washing fluid Aqueous humour Arabidopsis thaliana Arterial plasma; Venous plasma Arteries Artificial sea water Astrocytes B-cells B cells Back of eye (choroid/RPE) Bacterial cells Bacterial culture supernatant bacterial media Bacterial Supernatant Biofilm Biopsy Bladder Blank/QC Blastocysts Blood Blood (isolated platelets) Blood (plasma) Blood (plasma); Large Intestine Blood (plasma); Tumor tissue Blood (serum) Blood (serum) ; Liver Blood (serum) and blood (plasma) Blood (serum) and Liver Blood (serum); Urine; Brain; Kidney; Liver; Lung; Spleen Blood (whole) blood, feces, hippocampus, brainstem Blubber Bone Bone and bone marrow Bone marrow Bone marrow (Blood); Kidney (Tissue) Brain Brain - Cerebral Hemisphere Brain cortex Brain organoids Brain; Spinal cord; Serum Breast Breast cancer cells Breast milk Breast tissue Breath Bronchoalveolar lavage Brown adipose Brown fat tissue Cardiac tissue Cardiomyocyte cells Cecum Cell culture media Cell culture supernatant Cells Cerebral Cortex Cerebrospinal fluid CH12 B lymphoma cells Chili Pepper (Capsicum Chinense) CHO cells Choroid Plexus Colerectal cancer cells Colon colorectal tissue Conditioned treatment media Coral nubbins Cord blood Cord blood (serum) Corpus Luteum Cortex CSF CSF, Liver, serum Culture Media Cultured cells Cultured Colerectal cancer cells Cultured diatom cells Cultured fibroblasts Cultured human myotubes with Toxoplasma gondii Cultured kidney cells Cultured plankton cells Cultured primary cells Cultured Prochlorococcus cells and vesicles Cyst fluid Date palm fruit Dendritic cells Diatom cells/Particulate matter from sea ice cores Diet Digestive fluid Dissected organizer from Xenopus laevis Dorsal root ganglia DRG Dried long pepper Dry Blood Spot Duodenum E. coli EBC(Exhaled breath condensate) Eggs Embryo Embryonic cells Endothelial cells Enzymatic assay Epididymal adipose tissue Epithelial cells Erythrocytes Esophagus Exhaled Breath condensate Exhaled breath condensate; Bronchoalveolar lavage fluid Extracellular fluid Eye tissue Face Faecal samples Feces feces, hippocampus, brainstem Feces, Plasma Feces; Blood (serum) Femoral muscle fetus blood or cardiac blood Fibroblast cells Fibroblasts Fibrous root Fish larvae Flushing Fly Follicular fluid food Foreskin Fruit juice Fungal cells Fungal mycelium Fungal/bacterial volatiles Gastrocnemius Glioblastoma cells Glioma cells Head and neck Cancer cell line Head tissue Heads Heart Heart and Liver HEK cells HeLa cells Hemolymph Hep G2 cells Hepa 1 cells HepG2 cells Hindbrain Hippocampus HuH-7 cells Human breast epithelial and adipose tissue Human monocyte-derived macrophages (hMDM) human osteosarcoma cell line Hypothalamus ICC13-7 ICC13-7 xenograft Ileum in vitro reaction infected Red Blood Cells Insect brain Insect tissue Interstitial fluid Interstitial Fluid Intestinal lumen contents Intestine Intestine content; Liver; Spleen; Urine; Peritoneal fluid; Blood (serum) iPSC cells Jejunum Jurkat cells, Clone E6-1 K562 Cells Keratinocytes Kidney Kidney cortex Kidney epithelial cells Kidney outer medulla Kidney; Serum Larvae Larvae, CNS Larval Fish Heads/Brain Latex Leaf Leaf leachate Leaves Leukemia cells Liver liver, cecal content, urine Liver; Brain; Kidney Liver; Lymph node; Lung; Spinal; Peritoneal Liver; Plasma Liver; Spleen; Gut LnCap cells LNCaP cells Lung Lung airways Lung organoids Lung tumors Lymph fluid Lymphoma cells Macrophages Maize kernel Maize starchy endosperm Media Melanoma cells Merozoites isolated from RBC Mesenchymal stromal cells Mesenteric lymph Microbial biofilm Microglia Milk Mitochondria Monocytes Mononuclear cells mouse lungs Mouse tissues and interstitial fluids Multiple Multiple tissues Muscle Muscle (Gastrocnemius) Muscle (Quadriceps) Muscle; Gonad tissue Mycelia in media Mycoplasma Nasal Polyp tissue Neuro2A cells Neurons Neutrophils Non-small cell lung cancer Non-small cell lung cancer cell lines Not applicable Nucleus accumbens Optic nerve Organoid Osteoclast Outer medulla kidney Ovarian cancer cells Ovaries Ovary Pancreas Pancreatic Islets Parasite Paw skin PDX GBM - mouse brain tumor section Perfusate Peripheral blood mono-nuclear cells Peritoneal fluid Peritoneal macrophages Pf infected RBCs Photosynthetic organism Phytoplankton Placenta Plankton cells Plant Plant leaves and roots Plant root tissue Plant roots Plant shoot tissue Plant tissue/Enzyme assay Plaque samples plasma Plasma plasma, adipose, liver, muscle, heart, kidney, intestine, adipose Plasmodium cells Platelets Pooled sample Prostate Prostate cancer cells Proximal tubular cells queen bee head Rat Vena Cava Powder Rectum Red blood cells Renal cancer cells Renal tissue Retina Retina, back of the eye (choroid/RPE) Retinal ganglion cells Rhizome Rice grain Root Saliva Sarcoma Scalp Sciatic nerve Seawater Seaweed Seedlings Seeds Seminal plasma serum Serum Sewage sludge Shrimp organs SI Skeletal muscles Skeletal myotubes Skin Skin Biopsy Small intestinal fecal contents Small intestine SNU-668 Erastin-resistant cells Soil Spermatozoa Spinal cord Spleen Spleen; T-cells Splenocytes Sputum Stage 43 tadpoles Standard phosphatidylcholines Staphylococcus epidermidis intracellular Stem cells Stem cells culture media Stomach sub ventricular zone tissue Subcutaneous tumor tissues of pancreatic cancer Suspended Marine Particulate Matter Sweat synthetic Synthetic T-cells Tails Tear Testis testis, ovary, buccal gland, blood, and notochord Thyroid tissue Tissue Tissue homogenate Tissue; Skeleton Tongue tissue Total bone marrow flush (cells) Toxoplasma gondii Tumor allograft Tumor cells Tumor, Interstitial fluid Tumor, Pancreas & Plasma Tumor, plasma U2OS cells Ulcer biopsies Unspecifed Unspecified Urine urine, plasma, kidney cortex Uterine fluid Uterine flushing Uterus Vaginal epithelium Vastus lateralis Ventricles; Blood (plasma); Skeletal muscle; Liver; Epididymal fat Ventricles; Skeletal muscle; Subcutaneous fat Vitreous Wastewater White adipose White adipose tissue White adipose,Brown adipose,Heart,Liver,Pancreas Whole animals Whole bodies Whole insect Whole invertebrate animal Whole plant Whole tissue Whole worm extract Whole worm lysate Wine Worms Yeast cells Zebrafish	Select disease/phenotype category Select disease/phenotype

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Please address questions/issues/bugs regarding MetGENE to susrinivasan[AT]ucsd[dot]edu, mano[AT]sdsc[dot]edu